Question: What are the optics on the Xenium Analyzer?
Answer: The instrument is fully automated and combines powerful optics, data acquisition and decoding technology to detect analytes at high speed and resolution across the entire imageable area. The imager uses a high numerical aperture and a fast area scan camera with a low read noise sensor to capture image data at 212.5 nm per-pixel. Optical sectioning is performed along the Z axis to acquire data throughout the depth of the tissue, supporting thicknesses of 10 um in fresh-frozen and 5 um in FFPE tissues. The acquired images are processed through the Xenium Analysis software to enable single molecule detection of rolling circle amplification (RCA) products with ~30 nm lateral (XY) localization precision. Additionally, the instrument integrates sample handling, liquid handling, and wide-field epifluorescence imaging. Analyte detection and image acquisition are performed on the Xenium Analyzer in cycles.
Products: Xenium Analyzer