Question: Can an alternative RNase Inhibitor be used with the Chromium Nuclei Isolation Kit?
Answer: Not all RNase inhibitors perform the same, and not all have been validated with 10x Genomics assays. Some RNase inhibitors have been shown to have a negative impact on single-cell assays. Utilize the validated RNase inhibitor that is provided for the best results in your sequencing assays.
Using an alternative RNase inhibitor is not supported and is at your own risk.
Products: Single Cell Gene Expression, Single Cell Immune Profiling, Single Cell ATAC, Single Cell Multiome ATAC + GEX, Fixed RNA Profiling