Question: Is it normal to observe bright patches on the bottom surface of Chromium chips?
Answer: Yes, it is normal to observe bright patches on the bottom surface of Chromium chips. These are air pockets and may be visible by eye or under a microscope.
These air pockets are a normal and expected outcome of the chip manufacturing process. They do not have any functional impact on chip performance.
Example images can be found below.
Products: Universal 3' Gene Expression, Universal 5' Gene Expression, Flex Gene Expression, Epi ATAC, Epi Multiome ATAC + Gene Expression.