Question: Can I detect SNP's with the Single Cell DNA application?
Answer: At the Single Cell level, our recommended sequencing depth is 750,000 read pairs/cell. For human-sized genomes this means that 0.05x coverage per cell (human) is sequenced. At this sequence depth not every position of the genome is covered with enough sequence reads to allow for accurate variant calling. For this reason, SNP discovery is not currently supported in our SC DNA solution.
Products: Single Cell DNA