Question: Can I run non-human samples?
Answer: Human and mouse samples are compatible with the Single Cell DNA workflow. We haven’t tested other species, although they may be compatible. For microbial or plant samples, the cell wall may not efficiently lyse during the Cell Bead processing steps, making the DNA inaccessible to barcoding and amplification.
Only human and mouse reference genomes are supplied as pre-built references for use with the Cell Ranger DNA pipeline. For other species, a custom reference must be generated. For genomes much smaller or much larger than human, the software has not been optimized for CNV calling.
Products: Single Cell DNA