Question: Can IgA1 and IgA2 be detected in the Single Cell V(D)J assay?
Answer: Yes, the Cell Ranger algorithm is able to distinguish between IGHA1 and IGHA2. As seen in one of our public datasets (NSCLC B cells), both IGHA1 and IGHA2 genes are annotated:
In general, de novo assembly of V(D)J transcripts enables you to detect small differences between transcripts.
Products: Single Cell Immune Profiling