Question: Will the fluorescent signal from the segmentation stain interfere with the detection of genes?
Answer: No. The gene read-out and segmentation readout occur in different imaging cycles and utilize different detection systems. As part of the Xenium Multi-Tissue Stain Mix add-on kit, we will be providing a separate set of decoding reagents to increase specificity between gene detection and cell segmentation detection and mitigate any signal cross-talk.
Product: Xenium In Situ, Multimodal Cell Segmentation