Question: Is there a common 5’UTR captured during V(D)J enrichment?
Answer: Our V(D)J assay captures all the 5' UTRs that are present, but it doesn't rely on a common 5' UTR sequence for capture. Since the V gene family expands by duplication, there are likely some V genes with similar UTRs. But because the 5' UTR is non-coding, it mutates and diverges faster over time and we do not rely on UTR sequence homology for capture.
Products: Single Cell Immune Profiling