Question: Which MHC alleles can be used with Barcode Enabled Antigen Mapping (BEAM)?
Answer: 10x Genomics offers MHC Monomer kits with the following MHC class I alleles:
We have not tested other MHC alleles with the BEAM assay. At this time, we do not have plans to release additional MHC Monomer kits with other alleles.
While it may theoretically be possible for customers to provide their own biotinylated MHC monomers representing other MHC alleles, this is untested and unsupported. The concentration of the biotinylated MHC monomers in the 10x Genomics kits is proprietary.
Products: Single Cell Immune Profiling, Barcode Enabled Antigen Mapping (BEAM)